12. What is a C value? What is the relationship between C value and morphologicalcomplexity? What is a C-value paradox?13. What is the relationship between a non-Mendelian inheritance pattern and genes localized tothe DNA of the mitochondrial genome?14. What is an interactome? Why it would be important to understand the interactome in termsof designing drugs to treat metabolic diseases?15. What are some of the genetic consequences of having a transposable element invade a naïvegenome?16. What is the relationship between whole-genome sequencing and personalized medicine? 17. Why does having a variant allele associated with a disease not always guarantee that youwill get the disease? What other factors can influence the disease state?18. Many scientists believe that the ethical concerns about engineering a population of “geneticelites” are far in our future. What is it about the traits of intelligence and physical abilitythat are responsible for this belief? Is the development of CRISPR/Cas9 a game changer? 19. What are telomeres? Why do they shorten after each cell division. How is telomereshortening prevented in some cell types? What are these cell types?.20. What chemical modification happens to N-terminal histone tails to make the nucleosomegrip DNA tighter or looser?21. Define the semiconservative and semi-discontinuous nature of DNA replication. How doessemi-discontinuous relate to 5′ to 3′ polymerization and Okazaka fragments?
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